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Selective Internal Radiation Therapy (SIRT): SIR-Spheres

Patient Information -- Next Steps

microscopic radioactive beads

These microscopic radioactive beads, called SIR-Spheres®, deliver radiation directly to the tumor site while sparing surrounding tissue.

Patients interested in receiving Selective Internal Radiation Therapy (SIRT) should Fax the appropriate medical records to the UMGCC referral coordinator. (Please see Records Required for Evaluation).  We will respond within a few days regarding eligibility for the treatment.

If a patient is eligible, he/she will come to UMGCC in Baltimore for evaluation, which will include the following tests:

A team of specialists will consult with the patient, including liver cancer experts in medical oncology, radiation oncology, and interventional radiology.

If the above tests confirm eligibility for SIR-Spheres treatment, the patient will receive the first SIR-Spheres® infusion within three weeks.

SIR-Spheres® infusions are performed as an outpatient procedure. Treatment usually consists of two treatments, one each to the right and left lobe of the liver, given at least four weeks apart.

Follow-up treatment includes a Bremsstrahlung scan (Nuclear Medicine) within 24 hours of the SIR-Spheres procedure, blood work at two week intervals, and CT/MRI scans four weeks after the treatment.  A follow-up PET/CT scan is typically done six weeks after the second treatment.

Learn more about SIRT:

This page was last updated on: August 25, 2011.

For more information, please contact our SIR-Spheres coordinator, Svetlana Kudryasheva, at 410-328-8017.