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Research: Shared Services

Translational Laboratory

Relevant Research Publications

For More Information

  1. Burger, A.M., Dai, F., Schultes, C.M., Reszka, A.P., Moore, M.J., Double, J.A., Neidle, S. The G-quadruplex interactive molecule BRACO19 inhibits tumor growth, consistent with telomere binding and interference with telomerase function. Cancer Res. 65:1489-96 2005

  2. Cookson, J.C., Dai, F., Smith, V., Heald, R.A., Laughton, C. A., Stevens, M.F.G., Burger, A.M. Pharmacodynamics of the G-quadruplex-stabilizing telomerase inhibitor 3,11-difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium methosulfate (RHPS4) in vitro: activity in human tumor cells correlates with telomere length and can be enhanced, or antagonized, with cytotoxic agents. Mol. Pharmacol. 68: 15551-15558, 2005

  3. Burger, A.M., Kelland, L.R. Telomere Targeting Agents. In: Dawson, N., Kelly (Eds.) Prostate Cancer: Translational and Emerging Therapies, chapter 13, Taylor & Francis Group, LLC, New York, [in press]

  4. Burger, A.M., Gao, Y., Amemiya, Y., Kahn, H.J., Kitching, R., Yang, Y., Sun, P., Narod, S.A., Hanna, W.M., Seth, A.K. A novel breast cancer associated RING-type ubiquitin ligase correlates with outcome in invasive breast cancer. Cancer Res. 65: 10401-10412, 2005

  5. Burger, A.M., Amemiya Y., Kitching, R., Seth, A.K. Novel RING E3 Ubiquitin Ligases in Breast Cancer. Neoplasia 8:689-95, 2006

  6. Burger, A.M. Highlights in experimental therapeutics. Cancer Lett. Apr 26; [Epub ahead of print], 2006

Inter Programmatic Publications:

  1. Nandi S., Yu, J., Burger, A.M., Reinert, L.S., Gartenhaus, R.B. Expression of DNA mismatch repair proteins in transformed non-Hodgkin’s lymphoma: Relationship to smoking. Leukemia-Lymphoma [in press]

  2. Burger, A.M., Kelland, L.R. Telomere Targeting Agents. In: Dawson, N., Kelly (Eds.) Prostate Cancer: Translational and Emerging Therapies, chapter 13, Taylor & Francis Group, LLC, New York, [in press]

Intra Programmatic Publications:

  1. Sausville, E.A., Burger, A.M. Contributions of Human Tumor Xenografts to Anticancer Drug Development. Cancer Res. 66 :3351-3354, 2006

  2. Hollingshead, M., Alley, M., Burger, A.M., Borgel, S., Pacula-Cox, C., Fiebig, H.H., Sausville, E.A. In vivo anti-tumor efficacy of 17-DMAG (17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride), a water-soluble geldanamycin derivative. Cancer Chemother. Pharmacol. 56: 115-125, 2005

  3. Smith, V., Sausville, E.A., Camalier, R.F., Fiebig, H.H., Burger, A.M. Comparison of 17-dimethylaminoethylamino-17-demethoxy-geldanamycin (17DMAG) to 17-allylamino-demethoxygeldanamycin (17AAG) in vitro: effects on Hsp90 and client proteins in melanoma models. Cancer Chemother. Pharmacol. 56: 126-137, 2005

This page was last updated on: January 17, 2008.