Research Programs

Stem Cells: Beyond Transplantation

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News Briefs


 

Publications:

France Carrier, Ph.D., Associate Professor in the Department of Radiation Oncology , published a paper in the Journal of Biological Chemistry entitled: "Functional Significance for an Heterogenous Ribonucleoprotein A18 (hnRNP A18) Signature RNA Motif in the 3'UTR of Ataxia Telangiectasia Mutated and Rad3-related (ATR) Transcript." Yang, R., Zhan, M., Nalabothula, N., Yang, Q., Indig, F.E., Carrier, F. J. Biol. Chem. March 19: 285 (12), 8887-8893, 2010.

Curt I. Civin, M.D., Samuelson Professor of Cancer Research and Director of the Center for Stem Cell Biology & Regenerative Medicine, is featured in the Winter, 2010 issue of the Medicine Bulletin in an article entitled "Stem Cells: Beyond Transplantation."

Anne Hamburger, Ph.D., Professor, Department of Pathology, Zhang, Y. Ali, TZ, Zhou, H, D'Souza, D Lu, Y Jaffe, J., Liu, Z , Passaniti, A, Hamburger, AW. "ErbB3 Binding Protein 1 (EBP1) is a Potent Repressor of the Metastasis-Associated Gene AGR2 in Prostate Cancer." Cancer Research. 70:240-248, 2010.

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Events, Lectures & Workshops:

Members of the Hematologic Malignancies Program at UMGCC presented at the American Association for Cancer Research (AACR) 101st annual meeting April 17-21, 2010, in Washington, D.C. The meeting, themed “Conquering Cancer Through Discovery Research,” highlighted novel approaches and technologies being used in the laboratory, innovative preclinical science, clinical trial results, and more. See a list of presentations by UMGCC faculty.

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New Awards:

The University of Maryland School of Medicine has received $12.3 million in National Institutes of Health (NIH) grants to renovate UMGCC's research laboratories and to build core facilities that will provide key support services to cancer researchers. The NIH’s National Center for Research Resources (NCRR) has awarded a $5 million C06 construction grant to renovate laboratories on the eighth floor of the School of Medicine’s Bressler Research Building at 655 W. Baltimore St. Another $7.3 million G20 Core Renovation, Repair and Improvement grant will be used to consolidate existing core laboratories and build new facilities on the sixth and seventh floors of the Bressler Building.

Ashraf Z. Badros, M.D., Professor, Department of Medicine, received a Dental and Craniofacial R21 grant from the National Institutes of Health for his work entitled. "Role of Salivary Bisphosphonates in Osteonecrosis of the Jaw in Myeloma Patients," in the amount of $189,000 for the period April 1, 2010 to March 31, 2012.

Kevin J. Cullen, M.D., Director, UMGCC, received two administrative supplements to the Cancer Center Support Grant (P30):  one to hire a new physician-scientist in the amount of $1,500,000 for the period of August 1, 2009, to July 31, 2010, and the second for pilot and grant programs to support developing shared services in the amount of $150,000 for the period of September 1, 2009 to August 31, 2011.

Amy Fulton, Ph.D., Professor, Department of Pathology, and director of Hormone Responsive Cancer Program, received notice of a Susan G. Komen Foundation award for her work entitled "Prostaglandin E EP1 Receptor in Breast Cancer Metastasis" in the amount of $180,000 for three years from May 1, 2010, to April 30, 2013. Dr. Fulton is officially the PI on this award; Jocelyn Reader, Ph.D., the postdoctoral Fellow in her lab, will actually be the recipient of this award.

Ronald Gartenhaus, M.D., Associate Professor, Departments of Medicine and Molecular Microbiology & Immunology, received an NIAAA R01grant from the National Institutes of Health for his work entitled, “Alcohol Consumption and Risk of NHL: Role of mTOR Dysfunction”  in the amount of $1,781,250 for the period September 5, 2009 to August 31, 2014.

Drs. Baer, Rassool and Tomkinson

Drs. Baer, Rassool and Tomkinson recently have been awarded a V Foundation grant to study DNA repair pathways in leukemia.

Anne Hamburger, Ph.D., Professor, Department of Pathology, has been awarded an NCI grant, “A Novel Therapy for HER2-Positive Hormone Refractory Breast Cancer” in the amount of $930,338 for the period of September 30, 2009 to August 31, 2011.

Dave Pauza, Ph.D., Professor, Department of Medicine and Institute of Human Virology, received a four-year $1,238,776 grant from the National Cancer Institute for his work entitled "Mechanisms for Depleting Tumor Immunity in AIDS." The goal of this research is to investigate intracellular signaling pathways that control cell functions, to uncover defects associated with HIV infection. Knowledge of these defects and potentially understanding the viral proteins responsible for these defects, is proximal to designing new therapy approaches to recover gd T cells in persons with HIV disease.

Feyruz Rassool, Ph.D., Associate Professor, Department of Radiology, has been awarded a V Foundation grant, “Targeting abnormal DNA Repair Pathways in Leukemia”  in the amount of $600,000 for the period of September 1, 2009 to August 31, 2012.

Alan Tomkinson, Ph.D., Professor, Department of Radiation Oncology, received a $99,992 equipment supplement under the American Recovery and Reinvestment Act of 2009 (ARRA) to his R01 National Institute of Health (NIH) grant entitled "Cellular Functions of Eukaryotic DNA Ligases." In addition, Dr. Tomkinson received a two-year $235,815 ARRA sub-award. He will be working with James Fishbein from UMBC on a project entitled "Nitrosamine Chemistry and Biochemistry." The Equipment grant is from December 17, 2009 to July 31, 2010 and the new sub-award is from September 30, 2009 to September 29, 2011.

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New Appointments:

Arnob Banerjee, M.D., Ph.D., has joined the UMGCC Hematologic Malignancies Program and was appointed Clinical Assistant Professor of Medicine, University of Maryland School of Medicine. Dr. Banerjee graduated from Brown University with a Sc.B. in chemistry, and earned a M.D./Ph.D. from the Columbia University College of Physicians and Surgeons in New York. Dr. Banerjee completed his residency in internal medicine at the Hospital of the University of Pennsylvania in Philadelphia, as well as a Fellowship in Hematology and Oncology at the same institution. He is board certified in internal medicine and hematology. Dr. Banerjee will specialize in treating patients with hematologic malignancies and will focus his research efforts on lymphocyte biology in the cancer center's tumor immunology research program.

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This page was last updated on: June 22, 2010.