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Events, Lectures & Workshops
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Events, Lectures & Workshops:

UMGCC research presentations at the American Society of Hematology Annual Meeting, December 3-7, in Orlando, Florida.

Maria R. Baer, M.D., Professor, Department of Medicine, and Karthika Natarajan, Ph.D., Mehmet Burcu, B.S. made a research presentation on Inhibition of the Serine/Threonine Kinase Pim-1 Has Anti-Proliferative Effects In Acute Myeloid Leukemia (AML) and Sensitizes Multidrug Resistant Cells to Chemotherapy.
Yi Ning, Ph.D., Associate Professor, Department of Pathology and Director, Cytogenetics Laboratory, Lei Yu, M.D., Jocelyn Reader, Ph.D., Ching Chen, M.D., Xianfeng Frank Zhao, M.D., Jung Sook Ha, Ph.D., Charles Lee, Ph.D., Teresa York, M.D., Ivana Gojo, M.D. and Maria R. Baer, M.D. Activation of a Novel Palmitoyltransferase through a t(6;14) Translocation In T/Myeloid Biphenotypic Leukemia and Subsets of Acute Myeloid Leukemia.
Ivana Gojo, M.D., Associate Professor, Department of Medicine, Alison Walker, M.D., Maureen Cooper, M.D., Eric J Feldman, M.D., Swaminathan Padmanabhan, M.B.B.S., M.S., Maria R. Baer, M.D., Jennifer Poon, PharmD., Karen Small, B.S.N., Da Zhang, M.S., Mariola Sadowska, Ph.D. and Rajat Bannerji, M.D., Ph.D. made a research presentation on Phase II Study of the Cyclin-Dependent Kinase (CDK) Inhibitor Dinaciclib (SCH 727965).
Mariola Sadowska, Ph.D., Deputy Director, UMGCC Translational Laboratory Shared Service, Nidal Muvarak, B.S., Rena G. Lapidus, Ph.D., Edward A. Sausville, M.D., Ph.D., Rajat Bannerji, M.D., Ph.D. and Ivana Gojo, M.D. made a research presentation on In Patients with Advanced Acute Leukemias. Single Agent Activity of the Cyclin-Dependent Kinase (CDK) Inhibitor Dinaciclib (SCH 727965) In Acute Myeloid and Lymphoid Leukemia Cells.
Dan P. Zandberg, M.D., Second Year Hematology/Medical Oncology Fellow, Jason Bierenbaum, M.D., Ivana Gojo, M.D, Michael L. Tidwell, C.R.N.P., Yi Ning, Ph.D., Xianfeng Frank Zhao, M.D., Ph.D., Amy J. Davidoff, M.S., Ph.D. and Maria R. Baer, M.D. made a research presentation on Tertiary Center Referral Patterns for Myelodysplastic Syndrome (MDS) Patients Are Suggestive of Age and Race Disparities.
Michael W. Evans, M.D., M.P.H., Third Year Hematology/Medical Oncology Fellow, Victoria S Giffi, M.D., Ann Zimrin, M.D. and John R. Hess, M.D., M.P.H. made a research presentation on Presentation, Treatment, and Outcome for Twenty Consecutive Patients with Human Immunodeficiency Virus (HIV) Associated Thrombotic Microangiopathies (TMA).
Feyruz Rassool, Ph.D., Assistant Professor, Department of Radiation Oncology, Dipika Gemani, M.S., Lisa A Tobin, Anju Singh, M.D., M.P.H., Maria R Baer, M.D., and Shyam Biswal, Ph.D., M.S. made a research presentation on The Dark Side of NRF2: Upregulation of NRF2 as a Mechanism for Resistance to Imatinib In CML.
Gorgun Akpek, M.D., Assistant Professor, Department of Medicine, Marcelo C. Pasquini, M.D., M.S., Manza-A Agovi, M.P.H., Brent Logan, Ph.D., Kenneth R. Cooke, M.D., Richard T. Maziarz, M.D., Vikas Gupta, M.D., M.R.C.P., F.R.C.Path., Hillard M. Lazarus, M.D., F.A.C.P., Gregory A. Hale, M.D., David I. Marks, M.B.B.S., Ph.D., Dipnarine Maharaj, M.D., Uday Popat, M.D., Matthew Carabasi, M.D., Martin Bornhaeuser, Brian J. Bolwell, M.D., Olle Ringden, M.D., Karen K Ballen, M.D., J. Douglas Rizzo, M.D., M.S., Philip L. McCarthy, M.D. and Vincent T Ho, M.D., made a research presentation on Spleen Status and Engraftment After Allogeneic Hematopoietic Stem Cell Transplantation (HCT).
Amy J. Davidoff, Ph.D., M.S., Assistant Professor in the School of Pharmacy, Sheila Weiss Smith, Ph.D., Maria R Baer, M.D., Xuehua Ke, M.A., Jason M Bierenbaum, M.D., Franklin Hendrick, B.S., Diane L. McNally, BSPharm, M.S. and Steven D. Gore, M.D. made a research presentation on Access to Care, Race and Education Are Key Determinants of Erythropoietin Stimulating Agent (ESA) Use In Myelodysplastic Syndromes (MDS).
Kara A. Scheibner, Ph.D., Assistant Professor, Department of Pediatrics and Center for Stem Cell Biology and Regenerative Medicine, Brie Teaboldt, Mary Claire Hauer and Curt I. Civin, M.D. The Mir-23a~Mir-27a~Mir-24 Cluster Acts as a Tumor Suppressor In Leukemias by Post-Transcriptional Regulation of 14-3-3 Proteins.

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Clinical Trial Participation:

New Advance in Breast Cancer Prevention Builds on Dr. Angela Brodie's Research

Dr. Saranya Chumsri Leads National Study of Novel Approach to Treat Triple Negative Breast Cancer

Pooled Safety Analysis From Phase (Ph) 1 and 2 Studies of Carfilzomib (CFZ) In Patients with Relapsed and/or Refractory Multiple Myeloma (MM). Ashraf Z. Badros, M.D., Professor, Department of Medicine, Seema B. Singhal, M.D., David Samuel diCapua Siegel, M.D., Ph.D., Thomas Martin, M.D., Ravi Vij, M.B.B.S., M.D., Michael Wang, M.D., Andrzej J. Jakubowiak, M.D., Ph.D., Sagar Lonial, M.D., Vishal Kukreti, M.D., F.R.C.P.C., Jeffrey A. Zonder, M.D., Alvin F. Wong, PharmD., Leanne McCulloch, Michael Kauffman, M.D., Ph.D., Ruben Niesvizky, M.D., Robert Z. Orlowski, M.D., Ph.D., A. Keith Stewart, M.B.ChB. and Sundar Jagannath, M.D.

A Phase I Study of PD 0332991: Complete CDK4/6 Inhibition and Tumor Response In Sequential Combination with Bortezomib and Dexamethasone for Relapsed and Refractory Multiple Myeloma. Ashraf Z. Badros, M.D., Professor, Department of Medicine, Ruben Niesvizky, M.D., Suzanne Lentzsch, M.D., Ph.D., Asher A. Chanan-Khan, M.D., Seema B. Singhal, M.D., Jeffrey A. Zonder, M.D., Ravi Vij, M.B.B.S., M.D., Xiangao Huang, Ph.D., Maurizio DiLiberto, Ph.D., Rachel Courtney, Ph.D., M. Naveed Shaik, Ph.D., Sindy T. Kim, B.S., Sophia Randolph, M.D., Ph.D., Scott A. Ely, M.D., M.P.H., and Selina Chen-Kiang, Ph.D.

Challenges for Conducting Clinical Trials Evaluating Maintenance Chemotherapy In Acute Myeloid Leukemia (AML): a Cancer and Leukemia Group B (CALGB) Study. Maria R. Baer, M.D., Professor, Department of Medicine, William Blum, M.D., Kate Donohue, Ph.D., Guido Marcucci, M.D., Daniel J. DeAngelo, M.D., Ph.D., Geoffrey L.Uy, M.D., Bayard L Powell, M.D., Wendy Stock, M.D., Jonathan E. Kolitz, M.D., Meir Wetzler, M.D., Eva Hoke, Barry K. Moser, Ph.D., and Richard A. Larson, M.D.

Subcutaneous Omacetaxine (OM) Treatment of Chronic Phase (CP) Chronic Myeloid Leukemia (CML) Patients Following Multiple Tyrosine Kinase Inhibitor (TKI) Failure. Maria R. Baer, M.D., Professor, Department of Medicine, Jorge E. Cortes, M.D., Meir Wetzler, M.D., Jeff Lipton, M.D., F.R.C.P.C., Franck E. Nicolini, M.D., Ph.D., Michele Baccarani, M.D., H. Jean Khoury, David Cram, Pharm.D., Eric D. Humphriss, B.A., Annie-Claude Benichou, M.D., Adam Craig, M.D., Ph.D., and Hagop M. Kantarjian, M.D.

Bosutinib as Third-Line Treatment for Chronic Phase Chronic Myeloid Leukemia Following Failure of Second-Line Therapy with Dasatinib or Nilotinib. Aaron P. Rapoport, M.D., Professor, Department of Medicine, H. Jean Khoury, Dong-Wook Kim, M.D., Andrey Zaritskey, Carlo Gambacorti-Passerini, Andreas Hochhaus, Juan Navarro, Pedro Enrique Dorlhiac-Llacer, Maria Zanichelli, Virginia Kelly, Nadine Besson, Trevor McMullan, Hagop M. Kantarjian, and Jorge E. Cortes.

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Education Presentations:

Curt I. Civin, M.D., Professor, Department of Pediatrics, Kara A. Scheibner, Ph.D., Diane Heiser, Ian M Kaplan, Wen-Chih Cheng, Ph.D., MinJung Kim, Ph.D., Shubhada Shashikant Bharne, Ph.D., and Sebastien Morisot, Ph.D. made an education presentation on "MicroRNA Maestros of Hematopoiesis." In the Scientific Program Session: MicroRNAs, and Myeloid Differentiation and Function.

Ann Zimrin, M.D., Professor, Department of Medicine, made an education presentation on "Best Practices Survey," in the Training Program Directors' Workshop.

Ann Zimrin, M.D., Professor, Department of Medicine, made an education presentation on "Hands-On Activity -- Life Is A Crapshoot," in the High School Student Symposium.

Douglas Ross, M.D., Professor, Department of Medicine, presented a poster "Implementation of Experiential, Competency-Based Palliative and End-of-Life Care Training for Internal Medicine Residents and Medical Oncology Fellows" at the American Association for Cancer Education (AACE) meetings October 18^th. It won 1^st Place for poster presentations and came with a $300 cash prize as well. A picture of Dr. Ross receiving the award from the AACE president-elect will be available soon. Others involved were Deborah W. Shpritz, Susan D. Wolfsthal, Ann B. Zimrin, M.D., Timothy J. Keay, M.D., Hongbin fang, Ph.D., Carl A. Schuett, Laura M. Stapleton, and David E. Weissman.

Dhan V. Kalvakolanu, Ph.D., Professor, Department of Microbiology and Immunology, was invited as a distinguished speaker to the 110 year celebration of Tongji Medical Center, Wuhan, China October 14-16, 2010. Dr. Kalvakolanu delivered a lecture on the discovery of GRIMs, a novel class of tumor suppressors and their role in tumor development on this occasion.

Ashraf Badros, M.D., Professor, Department of Medicine, and Ronald Gartenhaus, M.D., Associate Professor, Department of Medicine, were invited speakers in the Lymphoma and Myeloma 2010 International Congress on Hematologic malignancies in New York City, October 21-23. Dr. Badros presented "Osteonecrosis of the jaw: Prevention and treatment," and Dr. Gartenhaus presented "Key signal transduction pathways in lymphoma."

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Publications:

Ronald Gartenhaus, M.D., Associate Professor, Department of Medicine, published in Oncogene an article entitled "Ribosomal Protein S6 is Highly Expressed in Non Hodgkin Lymphoma and Associates with mRNA Containing a 5' Terminal Oligopyrimidine Tract," along with Hagner PR, Mazan Mamczarz K, Dai B, Balzer EM, Corl S, Martin SS, Zhao XF, Gartenhaus RB.

Bret A. Hassel, Ph.D., Associate Professor, Department of Microbiology and Immunology, Xiao-Ling Li M.D., Ph.D., Research Associate, and Heather J. Ezelle, Ph.D., Research Associate, published a review in Wiley Interdisciplinary Reviews: RNA, entitled "A central role for RNA in the induction and biological activities of type-1 interferons."

Bret A. Hassel, Ph.D., Associate Professor, Department of Microbiology and Immunology, received notice of a Maryland Proof of Concept Award entitled "Broad Spectrum antimicrobial activity by pharmacologic activators of RNase-L," in the amount of $135,000 (total cost) for the period March 22, 2010 to March 21 2011.

Bret A. Hassel, Ph.D., Associate Professor, Department of Microbiology and Immunology, received notice of an ARRA Administrative Supplement to his NIAID R01 Award entitled "Role of the antiviral ribonuclease RNase-L in the host antibacterial response." The supplement is for $134,552 (total cost) for the period August 1, 2010 to July 31, 2011.

France Carrier, Ph.D., Associate Professor of Radiation Oncology, was invited to speak by the Cambridge Healthtech Institute at the Eight International Discovery on Target meeting in Boston on November 2, 2010. Her talk was entitled, "The inherent epigenetic makeup of cancer cells predisposes them to HDAC inhibitors sensitization to conventional anticancer therapies."

Maria R. Baer, M.D., Professor, Department of Medicine, Yingqiu Xie, Mehmet Burcu, Douglas E. Linn, Yun Qiu, published an article in Molecular Pharmacology entitled, "Pim-1 Kinase Protects P-Glycoprotein from Degradation and Enables its Glycosylation and Cell Surface Expression." Molecular Pharmacology 2010 Aug: 78(2):310-8.

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This page was last updated on: June 9, 2011.