Dictionary of Cancer Terms
View in Spanish: Inhibidor de la poli (ADP-ribosa) polimerasa
Poly (ADP-ribose) polymerase inhibitor (PAH-lee (AY-DEE-PEE-RY-bose) puh-LIM-eh-rays in-HIH-bih-ter)
A substance
that blocks an enzyme involved in many functions of the
cell, including the repair of DNA damage. DNA damage may be
caused by normal cell actions, UV light, some anticancer
drugs, and radiation used to treat cancer. It may cause
cancer cells to die. It is a type of targeted
therapy. Also called PARP inhibitor.
Source: National Cancer Institute Dictionary of Cancer Terms, available at www.cancer.gov/dictionary.