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Dictionary of Cancer Terms

View in Spanish: Dosis máxima tolerada

Maximum tolerated dose (MAK-sih-mum TAH-leh-RAY-ted …)
The highest dose of a drug or treatment that does not cause unacceptable side effects. The maximum tolerated dose is determined in clinical trials by testing increasing doses on different groups of people until the highest dose with acceptable side effects is found. Also called MTD.

Source: National Cancer Institute Dictionary of Cancer Terms, available at www.cancer.gov/dictionary.