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Home >Information for Patients > Dictionary Index

Dictionary of Cancer Terms

De novo mutation
An alteration in a gene that is present for the first time in one family member as a result of a mutation in a germ cell (egg or sperm) of one of the parents, or a mutation that arises in the fertilized egg itself during early embryogenesis. Also called new mutation.



 
 
Source: National Cancer Institute Dictionary of Cancer Terms, available at www.cancer.gov/dictionary.