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Dictionary of Cancer Terms

View in Spanish: Anticuerpo monoclonal totalmente humano IMC-1121B anti-RFCEV

Anti-VEGFR-2 fully human monoclonal antibody IMC-1121B (AN-tee … ful-ee HYOO-mun MAH-noh-KLOH-nul AN-tee-BAH-dee …)
A substance being studied in the treatment of breast cancer that has come back. It binds to receptors for a protein called vascular endothelial growth factor (VEGF). This keeps VEGF from binding to the receptors and may stop the growth of new blood vessels that tumors need to grow. It is a type of antiangiogenesis agent and a type of monoclonal antibody. Also called IMC-1121B and ramucirumab.

Source: National Cancer Institute Dictionary of Cancer Terms, available at www.cancer.gov/dictionary.