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Dictionary of Cancer Terms

View in Spanish: Anticuerpo monoclonal del anti-FCT-beta GC1008

Anti-TGF-beta monoclonal antibody GC1008 (AN-tee MAH-noh-KLOH-nul AN-tee-BAH-dee )
A monoclonal antibody being studied in the treatment of kidney cancer, melanoma, and pulmonary fibrosis. Monoclonal antibodies are made in the laboratory and can locate and bind to substances in the body, including cancer cells. Anti-TGF-beta monoclonal antibody GC1008 binds to the protein transforming growth factor-beta (TGFβ) and may block the growth of cancer cells that make it. Also called GC1008.

Source: National Cancer Institute Dictionary of Cancer Terms, available at www.cancer.gov/dictionary.