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Dictionary of Cancer Terms

View in Spanish: Y 90 Zevalin

Y 90 Zevalin ( ZEV-uh-lin)
A radiolabeled monoclonal antibody that is used to treat certain types of B-cell non-Hodgkin lymphoma and is being studied in the treatment of other types of B-cell tumors. It is made up of the monoclonal antibody ibritumomab plus the radioisotope yttrium Y 90. It binds to the protein called CD20, which is found on B cells. The radiation in the yttrium Y 90 may kill the cancer cells. Y 90 Zevalin is a type of radiopharmaceutical. Also called IDEC-Y2B8, Y 90 ibritumomab tiuxetan, and yttrium Y 90 ibritumomab tiuxetan.



 
 
Source: National Cancer Institute Dictionary of Cancer Terms, available at www.cancer.gov/dictionary.