Dictionary of Cancer Terms
View in Spanish: VB4-845
VB4-845
A substance being studied in the treatment of certain types of head and neck cancer. VB4-845 is made by linking a monoclonal antibody fragment to a toxic protein that may kill cancer cells. It binds to EpCAM (a protein on the surface of epithelial cells and some types of cancer cells). Also called anti-EpCAM-Pseudomonas-exotoxin fusion protein and Proxinium.
Source: National Cancer Institute Dictionary of Cancer Terms, available at www.cancer.gov/dictionary.