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Dictionary of Cancer Terms

View in Spanish: VB4-845

A substance being studied in the treatment of certain types of head and neck cancer. VB4-845 is made by linking a monoclonal antibody fragment to a toxic protein that may kill cancer cells. It binds to EpCAM (a protein on the surface of epithelial cells and some types of cancer cells). Also called anti-EpCAM-Pseudomonas-exotoxin fusion protein and Proxinium.

Source: National Cancer Institute Dictionary of Cancer Terms, available at www.cancer.gov/dictionary.