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Dictionary of Cancer Terms

View in Spanish: TRAIL-R2

A protein on the surface of certain cells that binds another protein called TRAIL, which may kill some cancer cells. An increase in the amount or activity of TRAIL-R2 on cancer cells may kill more cells. Also called death receptor 5, DR5, TRAIL receptor 2, and tumor necrosis factor receptor superfamily member 10B.

Source: National Cancer Institute Dictionary of Cancer Terms, available at www.cancer.gov/dictionary.