Dictionary of Cancer Terms
View in Spanish: Proxinium
Proxinium (prok-SIH-nee-um)
A substance being studied in the treatment of certain types of head and neck cancer. Proxinium is made by linking a monoclonal antibody fragment to a toxic protein that may kill cancer cells. It binds to EpCAM (a protein on the surface of epithelial cells and some types of cancer cells). Also called anti-EpCAM-Pseudomonas-exotoxin fusion protein and VB4-845.
Source: National Cancer Institute Dictionary of Cancer Terms, available at www.cancer.gov/dictionary.