Dictionary of Cancer Terms
View in Spanish: HDAC
HDAC
An enzyme that
removes a small molecule called an acetyl group from
histones (proteins found in chromosomes). This changes the
way the histones bind to DNA and may affect its activity.
HDAC
inhibitors are being studied in the treatment of
cancer. Also called histone deacetylase.
Source: National Cancer Institute Dictionary of Cancer Terms, available at www.cancer.gov/dictionary.