A Part of the University of Maryland Medical Center

Connect with UMGCC
Facebook Twitter YouTube Blog iPhone
Email PageEmail page Print PagePrint page

Home >Information for Patients > Dictionary Index

Dictionary of Cancer Terms

View in Spanish: Proteína de fusión BCR-ABL

BCR-ABL fusion protein ( FYOO-zhun PRO-teen)
A protein made from pieces of two genes that get joined together. It is found in most patients with chronic myelogenous leukemia (CML), and in some patients with acute lymphoblastic leukemia (ALL) or acute myelogenous leukemia (AML). Inside the leukemia cells, the ABL gene from chromosome 9 joins to the BCR gene on chromosome 22 to form the BCR-ABL fusion gene, which makes the BCR-ABL fusion protein.



 
 
Source: National Cancer Institute Dictionary of Cancer Terms, available at www.cancer.gov/dictionary.