Dictionary of Cancer Terms
View in Spanish: Proteína de fusión BCR-ABL
BCR-ABL fusion protein ( FYOO-zhun PRO-teen)
A protein made from pieces of two genes that get joined together. It is found in most patients with chronic myelogenous leukemia (CML), and in some patients with acute lymphoblastic leukemia (ALL) or acute myelogenous leukemia (AML). Inside the leukemia cells, the ABL gene from chromosome 9 joins to the BCR gene on chromosome 22 to form the BCR-ABL fusion gene, which makes the BCR-ABL fusion protein.
Source: National Cancer Institute Dictionary of Cancer Terms, available at www.cancer.gov/dictionary.