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Hematologic Malignancies Program

Patient and Family Education

Childhood Acute Lymphocytic Leukemia

Symptoms and Diagnosis

The American Cancer Society estimates that 5,760 new cases of acute lymphocytic leukemia were diagnosed in the United States in 2009. Approximately 3,800 of these cases occurred in adults. Childhood acute lymphocytic leukemia is often difficult to diagnose. The early signs may be similar to the flu or other common diseases. A child should see a doctor if he or she has the following signs or symptoms that won't go away:

  • fever, weakness or tiredness
  • aching in the bones or joints
  • swollen lymph nodes

The doctor may order blood tests to count the number of each of the different kinds of blood cells. If the results of the blood tests are not normal, a doctor may do a bone marrow biopsy. During this test, a needle is inserted into a bone and a small amount of bone marrow is taken out and looked at under the microscope.

The doctor may also do a spinal tap in which a needle is inserted through the back to take a sample of the fluid that surrounds the brain and spine. The fluid is then examined under a microscope to see if leukemia cells are present, and the doctor can diagnose the type of leukemia and plan the best treatment for it.

The chance of recovery (prognosis) from acute lymphocytic leukemia depends on how the leukemia cells look under a microscope, how far the leukemia has spread, and the patient's age and general health.


This page was last updated on: January 29, 2010.


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