Treatment of childhood LCH lesions in bones around the ears or eyes may lower the risk of developing diabetes insipidus and other long-term problems. Treatment may include:
Treatment of spine or hip bone lesions that have weakened the bone and may lead to a broken bone in childhood LCH may include:
Treatment of two or more bone lesions may include:
Treatment of childhood LCH central nervous system lesions may include various combinations of the following:
Recurrent LCH is disease that cannot be detected for some time after treatment and then comes back. Treatment of recurrent childhood LCH in the skin, bone, lymph nodes, gastrointestinal tract, pituitary gland, or central nervous system (low-risk organs) may include:
Refractory LCH is disease that does not get better with treatment. Treatment of refractory childhood LCH in high-risk organs and in multisystem low-risk organs may include high-dose chemotherapy. Treatment of childhood LCH in multisystem high-risk organs that did not respond to chemotherapy may include stem cell transplant.
Progressive LCH is disease that continues to grow during treatment. Treatment of progressive childhood LCH in patients with multisystem disease may include anticancer drugs that have not been given to the patient before.
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