A Part of the University of Maryland Medical Center

• General Information About Myelodysplastic/Myeloproliferative Neoplasms
• Chronic Myelomonocytic Leukemia
• Juvenile Myelomonocytic Leukemia
• Atypical Chronic Myelogenous Leukemia
• Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable
• Stages of Myelodysplastic/Myeloproliferative Neoplasms
• Treatment Option Overview
• Treatment Options for Myelodysplastic/Myeloproliferative Neoplasms
• To Learn More About Myelodysplastic/Myeloproliferative Neoplasms

• Hematologic Malignancies Program

• Diagnosis and Treatment...
• Physicians and Staff
• Q&A with Dr. Maria Baer
• Patient Education...
• 
    Related Resources
• Clinical Trials
• Information for Patients

Treatment Options for Myelodysplastic/Myeloproliferative Neoplasms

A link to a list of current clinical trials is included for each treatment section. For some types or stages of cancer, there may not be any trials listed. Check with your doctor for clinical trials that are not listed here but may be right for you.

Chronic Myelomonocytic Leukemia

Treatment of chronic myelomonocytic leukemia (CMML) may include the following:

• Chemotherapy with one or more agents.
• Stem cell transplant.
• A clinical trial of a new treatment.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with chronic myelomonocytic leukemia. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

Juvenile Myelomonocytic Leukemia

Treatment of juvenile myelomonocytic leukemia (JMML) may include the following:

• Combination chemotherapy.
• Stem cell transplant.
• 13-cis-retinoic acid therapy.
• A clinical trial of a new treatment, such as targeted therapy.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with juvenile myelomonocytic leukemia. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

Atypical Chronic Myelogenous Leukemia

Treatment of atypical chronic myelogenous leukemia (aCML) may include chemotherapy.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with atypical chronic myeloid leukemia, BCR-ABL1 negative. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable

Because myelodysplastic/myeloproliferative neoplasm, unclassifiable (MDS/MPN-UC) is a rare disease, little is known about its treatment. Treatment may include the following:

• Supportive care treatments to manage problems caused by the disease such as infection, bleeding, and anemia.
• Targeted therapy (imatinib mesylate).

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with myelodysplastic/myeloproliferative neoplasm, unclassifiable. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.