A Part of the University of Maryland Medical Center

• General Information About Vulvar Cancer
• Stages of Vulvar Cancer
• Recurrent Vulvar Cancer
• Treatment Option Overview
• Treatment Options by Stage
• Treatment Options for Recurrent Vulvar Cancer
• To Learn More About Vulvar Cancer

• Gynecologic Oncology Program

• Diagnostic and Treatment Services
• Physicians and Staff
• Patient Education...
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    Related Resources
• Baltimore City Cancer Program
• Cigarette Restitution Fund Program
• Clinical Trials
• Information for Patients

Treatment Options by Stage

A link to a list of current clinical trials is included for each treatment section. For some types or stages of cancer, there may not be any trials listed. Check with your doctor for clinical trials that are not listed here but may be right for you.

Stage 0 (Carcinoma in Situ)

Treatment of stage 0 may include the following:

• Wide local excision and/or laser therapy.
• Skinning vulvectomy with or without skin grafting.
• Simple vulvectomy.
• Topical chemotherapy.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage 0 vulvar cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

Stage I Vulvar Cancer

Treatment of stage I vulvar cancer may include the following:

• Wide local excision.
• Radical local excision with removal of nearby lymph nodes.
• Radical vulvectomy and either removal of nearby lymph nodes or radiation therapy to the lymph nodes.
• Radiation therapy.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage I vulvar cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

Stage II Vulvar Cancer

Treatment of stage II vulvar cancer may include the following:

• Modified radical vulvectomy and removal of nearby lymph nodes or radiation therapy to the lymph nodes. Radiation therapy to the area of surgery may also be given.
• Radiation therapy.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage II vulvar cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

Stage III Vulvar Cancer

Treatment of stage III vulvar cancer may include the following:

• Modified radical vulvectomy and removal of nearby lymph nodes, with or without radiation therapy.
• Radical vulvectomy and removal of nearby lymph nodes, with or without radiation therapy.
• Radiation therapy followed by surgery.
• Radiation therapy with or without chemotherapy.
• A clinical trial of a new treatment.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage III vulvar cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

Stage IV Vulvar Cancer

Treatment of stage IV vulvar cancer may include the following:

• Radical vulvectomy and pelvic exenteration.
• Radical vulvectomy followed by radiation therapy.
• Radiation therapy followed by surgery, with or without chemotherapy.
• Radiation therapy with or without chemotherapy.
• A clinical trial of a new treatment.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage IV vulvar cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.